منابع مشابه
Electrophoretic mobility of supercoiled, catenated and knotted DNA molecules
We systematically varied conditions of two-dimensional (2D) agarose gel electrophoresis to optimize separation of DNA topoisomers that differ either by the extent of knotting, the extent of catenation or the extent of supercoiling. To this aim we compared electrophoretic behavior of three different families of DNA topoisomers: (i) supercoiled DNA molecules, where supercoiling covered the range ...
متن کاملStructural Alignments of pseudo-knotted RNA-molecules in polynomial time
An RNA molecule is structured on several layers. The primary and most obvious structure is its sequence of bases, i.e. a word over the alphabet {A, C, G, U}. The higher structure is a set of one-to-one base-pairings resulting in a two-dimensional folding of the one-dimensional sequence. One speaks of a secondary structure if these pairings do not cross and of a tertiary structure otherwise. Sin...
متن کاملMinimally Knotted Spatial Graphs are Totally Knotted
Applying Jaco’s Handle Addition Lemma, we give a condition for a 3-manifold to have an incompressible boundary. As an application, we show that the boundary of the exterior of a minimally knotted planar graph is incompressible.
متن کاملNovel display of knotted DNA molecules by two-dimensional gel electrophoresis
We describe a two-dimensional agarose gel electrophoresis procedure that improves the resolution of knotted DNA molecules. The first gel dimension is run at low voltage, and DNA knots migrate according to their compactness. The second gel dimension is run at high voltage, and DNA knots migrate according to other physical parameters such as shape and flexibility. In comparison with one-dimension...
متن کاملKnotted Solitons
The dynamical model on 3+1 dimensional space-time admitting soliton solutions is discussed. The proposal soliton is localized in the vicinity of a closed contour, which could be linked and/or knotted. The topological charge is Hopf invariant. Some applications in realistic physical systems are indicated. 2000 Mathematics Subject Classification: 35Q51, 35S35, 65C20, 81V25.
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ژورنال
عنوان ژورنال: Nature
سال: 1972
ISSN: 0028-0836,1476-4687
DOI: 10.1038/238358b0